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Category: ebooks | Author:

Modeling Tumor Vasculature: Molecular, Cellular, and Tissue Level Aspects and Implications
Modeling Tumor Vasculature: Molecular, Cellular, and Tissue Level Aspects and Implications
Published: 2011-11-22 | ISBN: 1461400511 | PDF | 420 pages | 10.69 MB

To profoundly understand biology and harness its intricacies for human benefit and the mitigation of human harm requires cross-disciplinary approaches that incorporate sophisticated computational and mathematical modeling techniques. These integrative strategies are essential to achieve rapid and significant progress in issues, in health and disease, which span molecular, cellular and tissue levels. The use of mathematical models to describe various aspects of tumor growth has a very long history, dating back over six decades. Recently, however, experimental and computational advances have improved our in the understanding of how processes act at multiple scales to mediate the development of tumor vasculature and drive the advancement of cancer. This book will showcase the development and utilization of new computational and mathematical approaches to address multiscale challenges associated with tumor vascular development. In Part I: Cell Signaling and Molecular Aspects of Tumor Blood Vessel Formation, it will be come clear that mathematical modeling can help to biochemically and biomechanically phenotype one of the most important cell types involved in cancer progression: vascular endothelial cells. When subverted by the tumor modulated environment, vascular endothelial cells form a new vascular supply capable of nourishing and translocating cancer cells to other tissues. The models in Part I illustrate the importance of quantitative approaches for gaining a deeper understanding of how normal and abnormal aspects of signal integration culminate in the cell proliferation, migration, and survival decisions that result in pathological tumor angiogenesis. The focus of Part II is the angiogenesis cascade and all of its complexities. Successful angiogenesis is mediated by the intricate interplay between biochemical and biomechanical mechanisms, including cell-cell and cell-matrix interactions, cell surface receptor binding, and intracellular signal transduction. A major challenge facing the cancer research community is to integrate known information in a way that improves our understanding of the principal underpinnings driving tumor angiogenesis and that will advance efforts aimed at the development of new therapies for treating cancer. The chapters in Part II will highlight several mathematical and computational approaches for that can potentially address this challenge. While the first two thirds of the book's chapters demonstrate how important insights can be gained by studying cell signaling and vascular morphology and function, the series of chapters in Part III: Whole Organ Modeling of Tumor Growth and Vasculature, will integrate vasculature development with tumor growth dynamics. These two processes strongly depend on one another in ways that can only be theoretically investigated by biophysical approaches that cut across several levels of biological organization and describe both the tumor and the developing vasculature as they co-evolve. The purpose of this edited volume is not to provide a comprehensive review of all modeling efforts that address tumor vascular modeling; instead, a variety of interesting and innovative mathematical modeling approaches for understanding the development and effects of tumor vasculature are highlighted in order to illustrate some of the emerging trends in the field.
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Brain Tumor Pathology

Brain Tumor Pathology: Current Diagnostic Hotspots and Pitfalls by Davide Schiffer
English | 9 Mar. 2006 | ISBN: 1402039972 | 271 Pages | PDF | 9 MB

Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics.
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Category: ebooks | Author:

Brain Tumor Pathology

Brain Tumor Pathology: Current Diagnostic Hotspots and Pitfalls by Davide Schiffer
English | 9 Mar. 2006 | ISBN: 1402039972 | 271 Pages | PDF | 9 MB

Since Bailey and Cushing (1926), all brain tumor classifications have been called histogenetic. The nosographic position that the tumor types progressively acquired in the classification systems derived from the resemblance of tumor cells to those of the cytogenesis, modified whenever new information became available from different biological research fields and especially from molecular genetics.
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"Research Directions in Tumor Angiogenesis" ed. by Jianyuan Chai

"Research Directions in Tumor Angiogenesis" ed. by Jianyuan Chai
ITAe | 2013 | ISBN: 9789535109631 | 300 pages | PDF | 16 MB

This book focuses on tumor angiogenesis written by highly experienced scholars from five different countries. It is the goal of this book to provide readers with an update on the molecular and cellular mechanisms of this biological process and hopefully to point out some new research directions for future therapeutic adventure.
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"Research Directions in Tumor Angiogenesis" ed. by Jianyuan Chai


Category: ebooks | Author:

"Research Directions in Tumor Angiogenesis" ed. by Jianyuan Chai

"Research Directions in Tumor Angiogenesis" ed. by Jianyuan Chai
ITAe | 2013 | ISBN: 9789535109631 | 300 pages | PDF | 16 MB

This book focuses on tumor angiogenesis written by highly experienced scholars from five different countries. It is the goal of this book to provide readers with an update on the molecular and cellular mechanisms of this biological process and hopefully to point out some new research directions for future therapeutic adventure.
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Tumors and Tumor-Like Lesions of the Hepatobiliary Tract General and Surgical Pathology

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract: General and Surgical Pathology
SpringerReference | Pathology | Oct 20 2016 | ISBN-10: 3319269542 | 3559 pages | pdf | 93.99 mb
Authors: Zimmermann, Arthur
Comprehensively covers liver tumor pathology by combining issues of general pathology and surgical pathology
Addresses all aspects of surgical pathology
Presents cell biologic and molecular features in detail
Offers a complete description of a rapidly evolving field

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Tumors and Tumor-Like Lesions of the Hepatobiliary Tract General and Surgical Pathology


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Tumors and Tumor-Like Lesions of the Hepatobiliary Tract General and Surgical Pathology

Tumors and Tumor-Like Lesions of the Hepatobiliary Tract: General and Surgical Pathology
SpringerReference | Pathology | Oct 20 2016 | ISBN-10: 3319269542 | 3559 pages | pdf | 93.99 mb
Authors: Zimmermann, Arthur
Comprehensively covers liver tumor pathology by combining issues of general pathology and surgical pathology
Addresses all aspects of surgical pathology
Presents cell biologic and molecular features in detail
Offers a complete description of a rapidly evolving field

Comments: 0
Tumor Microenvironment Study Protocols (Advances in Experimental Medicine and Biology)
Tumor Microenvironment: Study Protocols (Advances in Experimental Medicine and Biology)
By Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia
2016 | 308 Pages | ISBN: 3319266640 | PDF | 11 MB

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Tumor Microenvironment Study Protocols (Advances in Experimental Medicine and Biology)


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Tumor Microenvironment Study Protocols (Advances in Experimental Medicine and Biology)
Tumor Microenvironment: Study Protocols (Advances in Experimental Medicine and Biology)
By Constantinos Koumenis, Lisa M. Coussens, Amato Giaccia
2016 | 308 Pages | ISBN: 3319266640 | PDF | 11 MB

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Nervenchirurgie: Trauma, Tumor, Kompression

Nervenchirurgie: Trauma, Tumor, Kompression By Thomas Kretschmer, Gregor Antoniadis, Hans Assmus
2014 | 418 Pages | ISBN: 3642368948 | PDF | 30 MB
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Nervenchirurgie: Trauma, Tumor, Kompression


Category: ebooks | Author:

Nervenchirurgie: Trauma, Tumor, Kompression

Nervenchirurgie: Trauma, Tumor, Kompression By Thomas Kretschmer, Gregor Antoniadis, Hans Assmus
2014 | 418 Pages | ISBN: 3642368948 | PDF | 30 MB
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Imaging of Complications and Toxicity following Tumor Therapy

Imaging of Complications and Toxicity following Tumor Therapy
Springer | Medicine | December 11, 2015 | ISBN-10: 331912840X | 314 pages | pdf | 22.8 mb

by Hans-Ulrich Kauczor (Editor), Tobias Bäuerle (Editor)
Describes the imaging appearances of therapy-induced complications and toxicities in oncologic patients
Identifies the potential impacts of therapy on all the major organs
Facilitates early recognition and differential diagnosis of complications and toxicities
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Imaging of Complications and Toxicity following Tumor Therapy


Category: ebooks | Author:

Imaging of Complications and Toxicity following Tumor Therapy

Imaging of Complications and Toxicity following Tumor Therapy
Springer | Medicine | December 11, 2015 | ISBN-10: 331912840X | 314 pages | pdf | 22.8 mb

by Hans-Ulrich Kauczor (Editor), Tobias Bäuerle (Editor)
Describes the imaging appearances of therapy-induced complications and toxicities in oncologic patients
Identifies the potential impacts of therapy on all the major organs
Facilitates early recognition and differential diagnosis of complications and toxicities
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The Tumor Microenvironment: Methods and Protocols

Josie Ursini-Siegel, Nicole Beauchemin, "The Tumor Microenvironment: Methods and Protocols"
English | ISBN: 1493937995 | 2016 | 369 pages | PDF | 13 MB
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The Tumor Microenvironment: Methods and Protocols


Category: ebooks | Author:

The Tumor Microenvironment: Methods and Protocols

Josie Ursini-Siegel, Nicole Beauchemin, "The Tumor Microenvironment: Methods and Protocols"
English | ISBN: 1493937995 | 2016 | 369 pages | PDF | 13 MB
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Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 3 edition

Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 3 edition (Childhood Cancer Guides) by Anne Spurgeon and Nancy Keene
English | 2016 | ISBN: 1941089909 | 576 pages | EPUB | 1,6 MB
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Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 3 edition


Category: ebooks | Author:

Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 3 edition

Childhood Cancer: A Parent's Guide to Solid Tumor Cancers, 3 edition (Childhood Cancer Guides) by Anne Spurgeon and Nancy Keene
English | 2016 | ISBN: 1941089909 | 576 pages | EPUB | 1,6 MB
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Handbook of Green Tea and Health Research


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Handbook of Green Tea and Health Research

"Handbook of Green Tea and Health Research" ed. by Helen Mckinley, Mark Jamieson
Food and Beverage Consumption and Health
N?v? Science Publishers | 2009| ISBN: 1607410451 9781607410454 | 520 pages | PDF | 16 MB

The scientific understanding of many biological functions involved in maintaining human health (e.g., role of gap junctions in homeostatic control of cell behaviors; multi-state nature of carcinogenesis; role of gap junctions in the tumor promotion step of carcinogenesis; toxicant induced oxidative stress in many human diseases; role of oxidative stress by tumor promoting chemicals; role of green tea components as anti-oxidants; preventive effects of green tea components on toxicant-inhibition of gap junction function and tumor promotion)
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Management of CNS Tumors


Category: ebooks | Author:


http://i54.fastpic.ru/big/2013/0405/d6/ca58274d7b22511296d4c4e80a347ad6.jpg
Management of CNS Tumors
English | ISBN: 9789533076461, 9533076461 | PDF | 474 Pages | 52 Mb

Management of CNS Tumors is a selected review of Central Nervous System (CNS) tumors with particular emphasis on pathological classification and complex treatment algorithms for each common tumor type. Additional detailed information is provided on selected CNS tumor associated disorders.
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Cancer Drug Resistance

Cancer Drug Resistance by Beverly A. Teicher
English | 9 Mar. 2006 | ISBN: 1588295303 | 636 Pages | PDF | 5 MB

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy.
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Cancer Drug Resistance


Category: ebooks | Author:

Cancer Drug Resistance

Cancer Drug Resistance by Beverly A. Teicher
English | 9 Mar. 2006 | ISBN: 1588295303 | 636 Pages | PDF | 5 MB

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy.
Comments: 0
Cancer Drug Resistance

Cancer Drug Resistance by Beverly A. Teicher
English | 9 Mar. 2006 | ISBN: 1588295303 | 636 Pages | PDF | 5 MB

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy.
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Comments: 0
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Cancer Drug Resistance


Category: ebooks | Author:

Cancer Drug Resistance

Cancer Drug Resistance by Beverly A. Teicher
English | 9 Mar. 2006 | ISBN: 1588295303 | 636 Pages | PDF | 5 MB

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy.
Comments: 0
Attempts to Understand Metastasis Formation I: Metastasis-Related Molecules (Current Topics in Microbiology and Immunology)

Attempts to Understand Metastasis Formation I: Metastasis-Related Molecules (Current Topics in Microbiology and Immunology) by Ursula Günthert
English | Jan. 1, 1996 | ISBN: 3642646972 | 301 Pages | PDF | 7 MB

In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The pu-rpose of these three volumes is to review the recent progress in molecular metas­ tasis research and to attempt to further understand the biol­ ogy of this multifocal process. With respect to present day molecular biology, the pioneers of metastasis research established the basic concepts of metasta­ sis formation in the 1970s and 1980s, namely, clonal selection of metastatic cells, heterogeneity of metastatic subpopulations, organ specificity of metastasis and the importance of angio­ genesis (Fidler, Kripke, Nicolson, Folkman and others).
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Attempts to Understand Metastasis Formation I: Metastasis-Related Molecules (Current Topics in Microbiology and Immunology)


Category: ebooks | Author:

Attempts to Understand Metastasis Formation I: Metastasis-Related Molecules (Current Topics in Microbiology and Immunology)

Attempts to Understand Metastasis Formation I: Metastasis-Related Molecules (Current Topics in Microbiology and Immunology) by Ursula Günthert
English | Jan. 1, 1996 | ISBN: 3642646972 | 301 Pages | PDF | 7 MB

In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The pu-rpose of these three volumes is to review the recent progress in molecular metas­ tasis research and to attempt to further understand the biol­ ogy of this multifocal process. With respect to present day molecular biology, the pioneers of metastasis research established the basic concepts of metasta­ sis formation in the 1970s and 1980s, namely, clonal selection of metastatic cells, heterogeneity of metastatic subpopulations, organ specificity of metastasis and the importance of angio­ genesis (Fidler, Kripke, Nicolson, Folkman and others).
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Attempts to Understand Metastasis Formation II: Regulatory Factors (Current Topics in Microbiology and Immunology)

Attempts to Understand Metastasis Formation II: Regulatory Factors (Current Topics in Microbiology and Immunology) by Ursula Günthert
English | Jan. 1, 1996 | ISBN: 3642646980 | 296 Pages | PDF | 9 MB

Within the last decade the molecular biology of tumor models has revealed the identification of several metastasis- related molecules. These volumes attempt to review the most recent approaches of their mechanisms, regulation and way to treat their malignant alterations. The first volume covers the presentation of proteases and inhibitors and their role in invasion of tumor cells, also cell adhesion molecules and their interaction with the extracellular matrix.
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Attempts to Understand Metastasis Formation II: Regulatory Factors (Current Topics in Microbiology and Immunology)


Category: ebooks | Author:

Attempts to Understand Metastasis Formation II: Regulatory Factors (Current Topics in Microbiology and Immunology)

Attempts to Understand Metastasis Formation II: Regulatory Factors (Current Topics in Microbiology and Immunology) by Ursula Günthert
English | Jan. 1, 1996 | ISBN: 3642646980 | 296 Pages | PDF | 9 MB

Within the last decade the molecular biology of tumor models has revealed the identification of several metastasis- related molecules. These volumes attempt to review the most recent approaches of their mechanisms, regulation and way to treat their malignant alterations. The first volume covers the presentation of proteases and inhibitors and their role in invasion of tumor cells, also cell adhesion molecules and their interaction with the extracellular matrix.
Comments: 0
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